RECQ5 rabbit pAb

The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],

Product Specifications

Background

UniProt

O94762

Swiss Prot

O94762

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human RECQ5 AA range: 647-697

Target

RECQ5

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

[Isoform Beta]: Nucleus, nucleoplasm . Nucleus . Recruited to sites of DNA damage, such as single-strand breaks and inter-strand cross-links, and at stalled replication forks. Re-localizes from the nucleolus into the nucleus after replicative stress and significantly associates with WRN during S-phase (PubMed:23180761) . .; [Isoform Alpha]: Cytoplasm .; [Isoform Gamma]: Cytoplasm .