3',4',7-Trimethoxyquercetin

3',4',7-Trimethoxyquercetin (Quercetin 3′,4′,7-trimethyl ether) is a polymethoxyflavonoid that can be isolated from Taraxacum mongolicum. 3',4',7-Trimethoxyquercetin is also a derivative of Quercetin hydrate (HY-18085A) . 3',4',7-Trimethoxyquercetin has anti-tumor activity[1][2][3].

Product Specifications

CAS Number

[6068-80-0]

Product Name Alternative

Quercetin 3′,4′,7-trimethyl ether

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

P-glycoprotein

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-4-7-trimethoxyquercetin.html

Purity

98.87

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=C1C(O)=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(OC)=CC(O)=C13

Molecular Formula

C18H16O7

Molecular Weight

344.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Shuyun Shi, et al. A high-speed counter-current chromatography- HPLC-DAD method for preparative isolation and purification of two polymethoxylated flavones from Taraxacum mongolicum. J Chromatogr Sc . May-Jun 2009;47 (5) :349-53.|[2]Scambia G, et al. Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother Pharmacol. 1994;34 (6) :459-64.|[3]Massi A, et al. Research Progress in the Modification of Quercetin Leading to Anticancer Agents. Molecules. 2017 Jul 29;22 (8) :1270.