RTC13
RTC13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy (DMD) [1].
Product Specifications
CAS Number
[1359825-94-7]
UNSPSC
12352005
Hazard Statement
H302
Target
Dystrophin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rtc13.html
Purity
98.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[N+](C1=C(C=CC=C1)C2=CC=C(/C=C3C(NC(S/3)=N)=O)O2)[O-]
Molecular Formula
C14H9N3O4S
Molecular Weight
315.30
Precautions
H302
References & Citations
[1]Refik Kayali, et al. Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy. Hum Mol Genet. 2012 Sep 15;21 (18) :4007-20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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