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Monoclonal Anti-Whitlow 218 linker Antibody, Rabbit IgG (P3C09), CF (carrier free), premium grade

Monoclonal Anti-Whitlow 218 linker Antibody, Rabbit IgG (P3C09), CF (carrier free), premium grade is a monoclonal antibody recombinantly expressed from HEK293 cells, which provides higher batch consistency and long term security of supply.

Product Specifications

Background

The whitlow/218 linker, with the sequence GSTSGSGKPGSGEGSTKG, is a commonly used synthetic peptide linker. Whitlow/218 linker often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The scFv containing the 218 linker showed reduced aggregation and was found to be more stable to proteolysis in vitro.

Host

HEK293

Target

218 linker

Conjugation

Unconjugated

Tag

Rabbit IgG | Rabbit Kappa

Applications

Flow Cytometry (Evaluation of CAR and SCFV containing 218linker on Human cells) .

Stability

2-8°C for 12 months under sterile conditions; -70°C for 24 months. For long term storage, the product should be stored at liquid state at -70°C.

Endotoxin

0.01 EU per μg

Purity

0.95

Format

Liquid

Buffer

PBS, pH7.4

Additives

Trehalose

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

500ug*1

Host or Source

HEK293

Species

Rabbit

Preservative

Trehalose

Frequently Asked Questions

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