Monoclonal Anti-Doxorubicin specific Antibody, Rabbit IgG (1M2C3)

Doxorubicin, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. As the payload of ADC drugs, Doxorubicin can act directly on DNA, insert into the double helix strands of DNA, cause the latter to unwind, change the template properties of DNA, and inhibit DNA polymerase, thereby inhibiting the synthesis of both DNA and RNA.. Anti-Doxorubicin antibody is a rabbit monoclonal antibody specifically reacts with Doxorubicin without other payloads, which is more sensitive than mouse antibody. The anti-Doxorubicin antibody is a useful reagent in PK assay to determine conjugated antibodies.