Polyclonal NG2/Cspg4 Antibody, Rabbit IgG
Polyclonal NG2/Cspg4 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.<br> Gene Synonyms: Cspg4, NG2, chondroitin sulfate proteoglycan 4, MCSP, MCSPG, Cspa, Cspg4a; 4732461B14Rik.
Product Specifications
Background
Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogenesis. In the central nervous system, NG2/Cspg4 is expressed in certain glia cells which are sometimes called polydendrocytes or oligodendrocyte precursor cells (OPCs), as well as in mesenchymal stem cells, osteoblasts, melanocytes, smooth muscle cells and macrophages. NG2/Cspg4-mediated signaling has been shown to play an important role in the progression of several tumor types including glioblastoma and malignant melanoma. NG2/Cspg4 is also a typical marker for vessel-surrounding pericytes, which contribute to the stabilization of microvessels, the regulation of capillary blood flow and angiogenesis.<br> Ampofo E, et al. Cell Mol Biol Lett. 2017;22:4. doi: 10.1186/s11658-017-0035-3.<br> General Notes: FOR RESEARCH USE ONLY.
Target
NG2/Cspg4
Conjugation
Unconjugated
Tag
Rabbit IgG
Stability
● Shipped at -20°C. Store at -20°C for 20 months; ● Shipped at -20°C. Store at -70°C for 3 years. Please avoid repeated freeze-thaw cycles.
Format
Liquid
Buffer
PH7.4, PBS, 65 mM Tris, 50 Mm Glycine
Additives
40% glycerol
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ul*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/NG4-S455.pdf
Species
Rabbit
Curated Selection
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