Human CCR8 Full Length Protein, His, Flag Tag (Nanodisc-pro)
Human CCR8 Full Length Protein, His, Flag Tag (CC8-H52D4) is expressed from human 293 cells (HEK293) . It contains AA Asp 2 - Ser 345 (Accession # P51685-1) .
Product Specifications
Background
This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs) . CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine) . It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.
Specifications
This protein .
Accession Number
P51685-1
Expression Region
Asp 2 - Ser 345
Host
HEK293
Target
CCR8
Conjugation
Unconjugated
Tag
N-10xHis & C-Flag
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Format
Liquid
Buffer
20 mM HEPES, 150 mM NaCl, pH7.5
Additives
Glycerol
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CC8-H52D4.pdf
Species
Human
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