Human CHRM2 Protein, Flag, His Tag (Detergent)
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Product Specifications
Background
Specifications
Accession Number
P08172-1
Expression Region
Met 1 - Asp 220 & Pro 377 - Arg 466
Host
HEK293
Target
CHRM2
Conjugation
Unconjugated
Tag
N-Flag & C-10xHis
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Purity
90%
Format
Liquid
Buffer
50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
Additives
Glycerol
Molecular Weight
50.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
500ug*1
Host or Source
HEK293
Species
Human
Protein ID
P08172-1
Preservative
Glycerol
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