Rat STEAP1 Protein, Flag, His Tag (Detergent)
Rat STEAP1 Protein, Flag, His Tag (ST1-R52D3) is expressed from human 293 cells (HEK293) . It contains AA Leu 43 - Leu 313 (Accession # D3ZEK7) .
Product Specifications
Background
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron (III) . Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
Specifications
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.6 kDa. The protein migrates as 30-31 kDa, 50-55 kDa and 65-70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
D3ZEK7
Expression Region
Leu 43 - Leu 313
Host
HEK293
Target
STEAP1
Conjugation
Unconjugated
Tag
N-Flag & C-10xHis
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Liquid
Buffer
50 mM HEPES, 150 mM NaCl, Buffer A, pH7.5
Additives
Glycerol
Molecular Weight
34.6 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/ST1-R52D3.pdf
Species
Rat
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