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Biotinylated Human Claudin-4 Full Length Protein, Avitag™, His&Flag Tag (Detergent)

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Product Specifications

Background

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Specifications

This protein carries an Avi tag (Avitag™) at the N-terminus followed a polyhistidine tag and at the C-terminus by a Flag tag. The protein has a calculated MW of 27.5 kDa. The protein migrates as 25 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Accession Number

O14493-1

Expression Region

Met 1- Val 209

Host

Insect Cells

Target

Claudin-4

Conjugation

Biotin-labeled

Tag

N-Avi & N-10xHis & C-Flag

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Purity

90%

Format

Liquid

Buffer

50 mM Tris, 150 mM NaCl, DDM, CHS, pH8.0

Additives

Glycerol

Molecular Weight

27.5 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

100ug*1

Host or Source

InsectCells

Species

Human

Protein ID

O14493-1

Preservative

Glycerol

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