Biotinylated Human CCR8 Protein, His, Flag&Avitag™ (Nanodisc)
Biotinylated Human CCR8 Protein, His, Flag&Avitag (CC8-H82D4) is expressed from human 293 cells (HEK293) . It is a membrane protein, contains complete wild type 7-transmembrane domans (TMD) and extracellular doman (ECD) .
Product Specifications
Background
This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs) . CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine) . It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.
Specifications
This protein carries a polyhistidine tag, followed by a Flag tag and an Avi tag (Avitag™) at the C-terminus. The protein has a calculated MW of 60.5 kDa.
Accession Number
P51685-1
Expression Region
Asp 2 - Ser 345
Host
HEK293
Target
CCR8
Conjugation
Biotin-labeled
Tag
C-10xHis & C-Flag & C-Avi
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Purity
90%
Format
Liquid
Buffer
20 mM HEPES, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
60.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ug*1
Host or Source
HEK293
Species
Human
Protein ID
P51685-1
Preservative
Trehalose
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