GMP Human DLL4 Protein, Fc Tag (Flagship)
GMP Human DLL4 Protein, Fc Tag (Flagship) (GMP-DL4H27) is expressed from human 293 cells (HEK293) . It contains AA Ser 27 - Pro 524 (Accession # NP_061947.1) .
Product Specifications
Background
Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 80.7 kDa. The protein migrates as 90 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
NP_061947.1
Expression Region
Ser 27 - Pro 524
Host
HEK293
Target
DLL4
Conjugation
Unconjugated
Tag
C-Fc
Stability
● -20°C to -70°C for 5 years in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
Endotoxin
10 EU/mg
Purity
95%
Format
Powder-GMP
Buffer
PBS, pH7.4
Molecular Weight
80.7 kDa
Shipping Conditions
Blue ice
Storage Conditions
-20°C
Package Size
200ug*5
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/GMP-DL4H27.pdf
Species
Human
Curated Selection
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