Dazukibart
Dazukibart (PF-06823859) is a potent, selective humanized IgG1 neutralizing monoclonal antibody that targets interferon β (IFNβ) . Dazukibart can be used in the study of moderate to severe dermatomyositis[1].
Product Specifications
CAS Number
[2639474-65-8]
Product Name Alternative
PF-06823859
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
IFNAR
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dazukibart.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
[Dazukibart]
Molecular Weight
(145.36 kDa)
Precautions
H302, H315, H319, H335
References & Citations
[1]Fiorentino D, et al. Efficacy, safety, and target engagement of dazukibart, an IFNβ specific monoclonal antibody, in adults with dermatomyositis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial. Lancet. 2025 Jan 11;405 (10473) :137-146.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Curated Selection
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