Sudoxicam
Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity[1][2][3].
Product Specifications
CAS Number
34042-85-8
UNSPSC
12352005
Hazard Statement
H301
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sudoxicam.html
Purity
99.96
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
OC(C1=CC=CC=C12)=C(C(NC3=NC=CS3)=O)N(C)S2(=O)=O
Molecular Formula
C13H11N3O4S2
Molecular Weight
337.37
Precautions
H301
References & Citations
[1]Obach RS, et al. In vitro metabolism and covalent binding of enol-carboxamide derivatives and anti-inflammatory agents sudoxicam and meloxicam: insights into the hepatotoxicity of sudoxicam. Chem Res Toxicol. 2008 Sep;21 (9) :1890-9.|[2] Wiseman EH, et al. Anti-inflammatory and pharmacokinetic properties of sudoxicam N- (2-thiazolyl) -4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide. Biochem Pharmacol. 1972 Sep 1;21 (17) :2323-34.|[3]Zhi-Yi Zhang. Sudoxicam. Handbook of Metabolic Pathways of Xenobiotics. September 2014.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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