Activated DPG Subunit

Activated DPG Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy[1].

Product Specifications

CAS Number

1155309-89-9

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Oligonucleotides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/activated-dpg-subunit.html

Purity

95.0

Solubility

DMSO : 5.71 mg/mL (ultrasonic)

Smiles

O=P(Cl)(N(C)C)OC[C@H](CN(C(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4)O[C@H]4N5C=NC6=C5N=C(NC(CC7=CC=CC=C7)=O)N=C6OCC(C=C8)=CC=C8OC(C(C)(C)C)=O

Molecular Formula

C51H53ClN7O7P

Molecular Weight

942.44

References & Citations

[1]Passini MA, et al. Exon skipping oligomer conjugates for muscular dystrophy. World Intellectual Property Organization, WO2018118599 A1. 2018-06-28.