D-687
Product Specifications
UNSPSC Description
D-687 is an inhibitor of Tau and Aβ. D-687 can reverse Aβ1–42-induced toxicity in SH-SH5Y cells and has significant neuroprotective properties[1].
Target Antigen
Amyloid-β; Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-687.html
Smiles
CC(N(C(C)C)CCN1CCN(CC1)C2=CC=C(C=C2)C3=CC=C(C(O)=C3)O)C
Molecular Weight
397.55
References & Citations
[1]Armstrong, et al. "Novel Piperazine Based Compounds Target Alzheimer’s Disease Relevant Amyloid β42 and Tau Derived Peptide AcPHF6, and the Lead Molecule Increases Viability in the Flies Expressing Human Tau Protein." ACS Chemical Neuroscience (2024).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169196/D-687-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169196/
Clinical Information
No Development Reported
CAS Number
2276762-06-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
