D-687
D-687 is an inhibitor of Tau and Aβ. D-687 can reverse Aβ1–42-induced toxicity in SH-SH5Y cells and has significant neuroprotective properties[1].
Product Specifications
CAS Number
2276762-06-0
UNSPSC
12352005
Target
Amyloid-β; Tau Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-687.html
Smiles
CC(N(C(C)C)CCN1CCN(CC1)C2=CC=C(C=C2)C3=CC=C(C(O)=C3)O)C
Molecular Formula
C24H35N3O2
Molecular Weight
397.55
References & Citations
[1]Armstrong, et al. "Novel Piperazine Based Compounds Target Alzheimer’s Disease Relevant Amyloid β42 and Tau Derived Peptide AcPHF6, and the Lead Molecule Increases Viability in the Flies Expressing Human Tau Protein." ACS Chemical Neuroscience (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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