TORC1/CRTC1 (phospho-Ser151) rabbit pAb

Product Specifications

Product Name Alternative

CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)

UniProt

Q6UUV9

Swiss Prot

Q6UUV9

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)

Target

TORC1

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Buffer

-20°C/1 year

Molecular Weight

70kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

70kD

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (PubMed:16817901) . Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (PubMed:15589160) . Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (By similarity) . .

Other Product Names

CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)