Nootkatone

Nootkatone, a neuroprotective agent from Vitis vinifera, has antioxidant and anti-inflammatory effects[1]. Nootkatone improves cognitive impairment in lipopolysaccharide-induced mouse model of Alzheimer's disease[2].

Product Specifications

CAS Number

[4674-50-4]

Product Name Alternative

(+) -Nootkatone

UNSPSC

12352211

Hazard Statement

H317

Target

Interleukin Related; TNF Receptor

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nootkatone.html

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C2CC[C@@H](C(C)=C)C[C@@]2(C)[C@H](C)C1

Molecular Formula

C15H22O

Molecular Weight

218.33

Precautions

H317

References & Citations

[1]Wang Y, et al. Nootkatone, a neuroprotective agent from Alpiniae Oxyphyllae Fructus, improves cognitive impairment in lipopolysaccharide-induced mouse model of Alzheimer's disease. Int Immunopharmacol. 2018 Sep;62:77-85.