Z-Arg-Arg-4MβNA (triacetate)

Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm) [1][2].

Product Specifications

CAS Number

[100900-19-4]

UNSPSC

12171500

Hazard Statement

H302-H315-H319-H335

Target

Cathepsin

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-arg-arg-4mβna-triacetate.html

Solubility

10 mM in DMSO

Smiles

CC(O)=O.COC1=CC(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(OCC2=CC=CC=C2)=O)=O)=O)=CC3=C1C=CC=C3.CC(O)=O.CC(O)=O

Molecular Formula

C37H53N9O11

Molecular Weight

799.87

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Büth H, et al. HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. Eur J Cell Biol. 2004 Dec;83 (11-12) :781-95.|[2]van den Bos T, et al. Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption: Special emphasis on collagen. Bone. 2008 Sep;43 (3) :459-68.