Ferroptosis inducer-6
Ferroptosis inducer 6 (6d) is a ferroptosis inducer with high potency for type I/-II photodynamic therapy by inducing ROS generation, oxidative stress and mitochondrial damage. Ferroptosis inducer 6 has anti-tumor activity[1].
Product Specifications
CAS Number
2933939-15-0
UNSPSC
12352005
Target
Ferroptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ferroptosis-in-13.html
Smiles
[F-][P+5]([F-])([F-])([F-])([F-])[F-].CC(C=C1C2=[N]3C=CC(CN4CCN(CC4)CC5=CC=CC=C5)=C2)=CC=[N]1[Ru+2]637([N]8=CC=C(C)C=C8C9=[N]7C=CC(CN%10CCN(CC%10)CC%11=CC=CC=C%11)=C9)[N]%12=CC=C(C)C=C%12C%13=[N]6C=CC(CN(CC%14)CCN%14CC%15=CC=CC=C%15)=C%13.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Molecular Formula
C69H78F12N12P2Ru
Molecular Weight
1466.44
References & Citations
[1]Zheng H, et al. Novel tris-bipyridine based Ru (II) complexes as type-I/-II photosensitizers for antitumor photodynamic therapy through ferroptosis and immunogenic cell death. Eur J Med Chem. 2024 Sep 24;279:116909.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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