ATG12-ATG3 inhibitor 1
ATG12-ATG3 inhibitor 1 (compound 189) is a potent inhibitor of autophage[1].
Product Specifications
CAS Number
[333351-38-5]
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atg12-atg3-inhibitor-1.html
Purity
99.31
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=S(NC1=CC=C(C2=C1C=CC=C2)O)(C3=CC=C(C)C=C3C)=O
Molecular Formula
C18H17NO3S
Molecular Weight
327.40
References & Citations
[1]Gal Chaim Nuta, et al. Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction. Autophagy. 2023 Aug;19 (8) :2372-2385.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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