GK16S

GK16S is a UCHL1 chemogenomic probe. GK16S can be used as a complement to GK13S. GK16S and GK13S can be used to study UCHL1 function in cells[1]. GK16S is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gk16s.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C#CCCCNC([C@H]1CCN(C#N)C1)=O

Molecular Formula

C11H15N3O

Molecular Weight

205.26

References & Citations

[1]Grethe C, et al. Structural basis for specific inhibition of the deubiquitinase UCHL1. Nat Commun. 2022 Oct 10;13 (1) :5950.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

P9103-19Y1 100 µg

Protein Kinase C, delta, phosphorylated (Ser645) (PKCd)

Ask

View Details

TA806978AM 100 µL

MMP3 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4C12]

Ask

View Details

P528251 100 µg

S100A9 Protein (Native, Human)

Ask

View Details

TRC-B016172-250MG 250 mg

Bis(2,5-dioxopyrrolidin-1-yl) succinate

Ask

View Details

GTR15197578 1 Vial

Lentiviral mouse Eef2k shRNA (UAS) - Lentiviral mouse Eef2k shRNA (UAS, GFP) plasmid

Ask

View Details

171598-APC 100 µL

Human Immunodeficiency Virus Type 1, p24 (HIV-1 p24) (APC)

Ask

View Details