GK16S
GK16S is a UCHL1 chemogenomic probe. GK16S can be used as a complement to GK13S. GK16S and GK13S can be used to study UCHL1 function in cells[1]. GK16S is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gk16s.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCCCNC([C@H]1CCN(C#N)C1)=O
Molecular Formula
C11H15N3O
Molecular Weight
205.26
References & Citations
[1]Grethe C, et al. Structural basis for specific inhibition of the deubiquitinase UCHL1. Nat Commun. 2022 Oct 10;13 (1) :5950.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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