L-Kynurenine-d4-1 (hydrochloride)
L-Kynurenine-d4-1 hydrochloride is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.58
Solubility
DMSO : 12.5mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 20mg/mL (ultrasonic)
Smiles
OC([C@@H](N)CC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])N)=O)=O.[H]Cl
Molecular Formula
C10H9D4ClN2O3
Molecular Weight
248.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Nozaki K, et al. Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J Cereb Blood Flow Metab. 1992 May;12 (3) :400-7.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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