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L-Kynurenine-d4-1 (hydrochloride)

L-Kynurenine-d4-1 hydrochloride is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.58

Solubility

DMSO : 12.5mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 20mg/mL (ultrasonic)

Smiles

OC([C@@H](N)CC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])N)=O)=O.[H]Cl

Molecular Formula

C10H9D4ClN2O3

Molecular Weight

248.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Nozaki K, et al. Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J Cereb Blood Flow Metab. 1992 May;12 (3) :400-7.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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