Exaluren (disulfate)

Exaluren (ELX-02) disulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG) . Exaluren disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations[1].

Product Specifications

CAS Number

[2244622-33-9]

Product Name Alternative

ELX-02 (disulfate) ; NB-124 (disulfate)

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/exaluren-disulfate.html

Concentration

10mM

Purity

98.0

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

OS(=O)(O)=O.C[C@@H](O)[C@@]([C@@H](O)[C@H](O)[C@H]1N)([H])O[C@]1([H])O[C@H]([C@H](C[C@@H](N)[C@@H]2O)N)[C@]2([H])O[C@@H]3O[C@@]([C@@H](N)C)([H])[C@@H](O)[C@H]3O.OS(=O)(O)=O

Molecular Formula

C19H42N4O18S2

Molecular Weight

678.68

References & Citations

[1]Leubitz A, et al. Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of ELX-02, a Potential Treatment for Genetic Disorders Caused by Nonsense Mutations, in Healthy Volunteers. Clin Pharmacol Drug Dev. 2019 Jan 16.