IDO1/TDO-IN-4
IDO1/TDO-IN-4 is a potent IDO1/TDO dual inhibitor, with IC50 values of 3.53 μM (IDO1) and 1.15 μM (TDO) . IDO1/TDO-IN-4 forms hydrogen bond with IDO1, and π π stacking interaction with TDO. IDO1/TDO-IN-4 can be used in the research of depression, and depression-induced infectious, metabolic, and autoimmune disorders[1].
Product Specifications
CAS Number
[461424-21-5]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ido1-tdo-in-4.html
Purity
99.74
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |Methanol : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C12=CC=CC=C1NC3=C2C=CN=C3C4=CNC=N4
Molecular Formula
C14H10N4
Molecular Weight
234.26
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1
Available Sizes
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