Dehydrocostus Lactone
Dehydrocostus Lactone ((-) -Dehydrocostus lactone) is a natural sesquiterpene that can be isolated from Saussurea lappa. Dehydrocostus Lactone has multiple activities such as anti-inflammatory, antibacterial, anti-tumor, and immunomodulatory effects. Dehydrocostus Lactone has an MIC of 2 µg/mL against Mycobacterium tuberculosis. Dehydrocostus Lactone can also inhibit the killing activity of cytotoxic T lymphocytes and induce apoptosis in tumor cells[1][2][3][4].
Product Specifications
CAS Number
477-43-0
Product Name Alternative
(-) -Dehydrocostus lactone; Epiligulyl oxide
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; Apoptosis; Bacterial; Caspase; Interleukin Related; MAPKAPK2 (MK2) ; NF-κB; NO Synthase; p38 MAPK
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Dehydrocostus-Lactone.html
Purity
99.98
Solubility
DMSO : 250 mg/mL (ultrasonic) |Ethanol : 15 mg/mL (ultrasonic)
Smiles
O=C(O[C@@]([C@@]1([H])C(CC[C@@]21[H])=C)([H])[C@@]3([H])CCC2=C)C3=C
Molecular Formula
C15H18O2
Molecular Weight
230.30
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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