exo-IWR-1
Product Specifications
UNSPSC Description
exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway[1][2].
Target Antigen
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/exo-iwr-1.html
Purity
98.75
Solubility
DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(N1C(C=C2)=CC=C2C(NC3=CC=CC4=C3N=CC=C4)=O)[C@@]5([H])[C@](C1=O)([H])[C@H]6C[C@@H]5C=C6
Molecular Weight
409.44
References & Citations
[1]Brooke Hamion, et al. Genome-wide RNA Interference Screen Identifies Novel Drug Targets for Rift Valley Fever Virus That Minimi the Potential for Drug Resistance.|[2]Brooke Harmon, et al. A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection. J Virol. 2016 Jul 27;90(16):7084-7097.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108437/exo-IWR-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108437/exo-IWR-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1127442-87-8
Available Sizes
Curated Selection
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