5-Dihydrocortisone

5-Dihydrocortisone is a 5-Dihydrocortisone with mixture of isomers. 5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver[1]

Product Specifications

CAS Number

[28423-48-5]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/5-dihydrocortisone.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2(O)C(CO)=O)([H])[C@@]3([H])[C@@](C(C1)=O)([H])[C@@]4(C(CC(CC4)=O)([H])CC3)C

Molecular Formula

C21H30O5

Molecular Weight

362.46

References & Citations

[1]Nikolaos Nikolaou, et al. AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells. J Steroid Biochem Mol Biol