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Diphenylpyraline (hydrochloride)

Diphenylpyraline hydrochloride is a potent histamine H1 receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.[1]

Product Specifications

CAS Number

132-18-3

Product Name Alternative

4-Diphenylmethoxy-1-methylpiperidine hydrochloride

UNSPSC

12352005

Hazard Statement

H302

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Diphenylpyraline-hydrochloride.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

CN1CCC(OC(C2=CC=CC=C2)C3=CC=CC=C3)CC1.[H]Cl

Molecular Formula

C19H24ClNO

Molecular Weight

317.85

Precautions

H302

References & Citations

[1]Erik B Oleson, et al. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward.|[2]Gennady B Lapa, et al. Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

H1 Receptor

Available Sizes

Frequently Asked Questions

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