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17:1 Lyso PC

17:1 Lyso PC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body[1][2].

Product Specifications

CAS Number

[1246304-62-0]

UNSPSC

12352211

Target

Liposome

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/17-1-lyso-pc.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCC/C=C\CCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Molecular Formula

C25H50NO7P

Molecular Weight

507.64

References & Citations

[1]Hyperactivators of mammalian dendritic cells. World Intellectual Property Organization, WO2022221827 A2 2022-10-20.|[2]Juliano R L, et al. Liposomes as a drug delivery system for antisense oligonucleotides[J]. Antisense research and development, 1992, 2 (2) : 165-176.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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