LY219703

LY219703 is a photoactivatable analogue of the antitumor diarylsulfonylurea sulofenur. LY219703 are distributed mainly in membranes, particularly those of organelles such as mitochondria[1].

Product Specifications

CAS Number

[156281-08-2]

UNSPSC

12352005

Target

Photosensitizer

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ly219703.html

Smiles

O=S(C1=CC=C(C=C1)N=[N+]=[N-])(NC(NC2=CC=C(C=C2)Cl)=O)=O

Molecular Formula

C13H10ClN5O3S

Molecular Weight

351.77

References & Citations

[1]Houghton PJ, et al. Characterization of the intracellular distribution and binding in human adenocarcinoma cells of N- (4-azidophenylsulfonyl) -N'- (4-chlorophenyl) urea (LY219703), a photoaffinity analogue of the antitumor diarylsulfonylurea sulofenur. Biochem Pharmacol. 1995 Mar 1;49 (5) :661-8.