Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DM3

Product Specifications

Product Name Alternative

Maytansinoid DM3

UNSPSC Description

DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].

Target Antigen

ADC Cytotoxin; Microtubule/Tubulin

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dm3.html

Purity

95.59

Solubility

DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCC(S)C)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

Molecular Weight

766.34

References & Citations

[1]Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130080/DM3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130080/DM3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

796073-54-6

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CECR5, ID (Cat Eye Syndrome Critical Region Protein 5) (PE)
MBS6468565-01 0.2 mL

CECR5, ID (Cat Eye Syndrome Critical Region Protein 5) (PE)

Ask
View Details
CECR5, ID (Cat Eye Syndrome Critical Region Protein 5) (PE)
MBS6468565-02 5x 0.2 mL

CECR5, ID (Cat Eye Syndrome Critical Region Protein 5) (PE)

Ask
View Details
IPL Peptide
abx269444 100 µg

IPL Peptide

Ask
View Details
Rabbit Anti-Human IL1RN pAb
PA10073-01 50 μL

Rabbit Anti-Human IL1RN pAb

Ask
View Details
Rabbit Anti-Human IL1RN pAb
PA10073-02 100 μL

Rabbit Anti-Human IL1RN pAb

Ask
View Details
Human TF Matched Antibody Pair Set [ABP-S-04687]
ABP-S-04687 5 Plates

Human TF Matched Antibody Pair Set [ABP-S-04687]

Ask
View Details