Methyl kakuol

Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1].

Product Specifications

CAS Number

[70342-29-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

TRP Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/methyl-kakuol.html

Solubility

10 mM in DMSO

Smiles

O=C(C(C=C(OCO1)C1=C2)=C2OC)CC

Molecular Formula

C11H12O4

Molecular Weight

208.21

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Takashi Matsumoto, et al. In Vivo Pharmacokinetic Analysis Utilizing Non-Targeted and Targeted Mass Spectrometry and In Vitro Assay against Transient Receptor Potential Channels of Maobushisaishinto and Its Constituent Asiasari Radix. Molecules. 2020 Sep 18;25 (18) :4283.