[D-Phe2,6, Pro3]-LH-RH
Product Specifications
UNSPSC Description
[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist[1].
Target Antigen
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/d-phe2-6-pro3-lh-rh.html
Solubility
H2O
Smiles
O=C(N[C@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@@H](CO)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@H](CC4=CC=CC=C4)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(NCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC6)NC6=O
Molecular Weight
1193.35
References & Citations
[1]Wilks JW, et al. Effect of [D-Phe2, Pro3, D-Phe6]-luteinizing hormone releasing hormone, an antagonist, on preovulatory gonadotropin secretion in the rhesus monkey. Biol Reprod. 1980 Aug;23(1):1-9.|[2]Loumaye E, et al. Homologous regulation of gonadotropin-releasing hormone receptors in cultured pituitary cells. Science. 1982 Feb 19;215(4535):983-5. |[3]Gian, et al. TRH, LHRH and Synthetic [D-Phe2-6, Pro3]-LHRH Stimulate in Vitro Thyrotropin Secretion by Crested Newt Pituitaries. TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY: FROM MOLECULAR TO INTEGRATIVE BIOLOGY. 1998;839(1):522-523.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3666/D-Phe2-6-Pro3-LH-RH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3666/
Clinical Information
No Development Reported
CAS Number
64789-67-9
Curated Selection
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