Enflicoxib
Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2) . Enflicoxib does not inhibit cyclooxygenase-1 (COX-1) . E-6087 shows anti-inflammatory, analgesic and antipyretic activities in animal models[1].
Product Specifications
CAS Number
[251442-94-1]
Product Name Alternative
E 6087
UNSPSC
12352005
Hazard Statement
H302, H373
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/enflicoxib.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=CC=C(N2N=C(C(F)(F)F)CC2C3=CC=C(F)C=C3F)C=C1)(N)=O
Molecular Formula
C16H12F5N3O2S
Molecular Weight
405.34
Precautions
H302, H373
References & Citations
[1]Carlos Pérez-Maseda, et al. Determination of enantiomeric purity of a novel COX-2 anti-inflammatory drug by capillary electrophoresis using single and dual cyclodextrin systems. Electrophoresis. 2003 May;24 (9) :1416-21. |[2]R F Reinoso, et al. Pharmacokinetics of E-6087, a new anti-inflammatory agent, in rats and dogs. Biopharm Drug Dispos. 2001 Sep;22 (6) :231-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
COX-2
Available Sizes
Curated Selection
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