L-Glutamine-d5

L-Glutamine-d5 is the deuterium labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

Product Specifications

CAS Number

[14341-78-7]

Product Name Alternative

L-Glutamic acid 5-amide-d5

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Ferroptosis; Isotope-Labeled Compounds; mGluR

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Purity

99.79

Solubility

H2O : 12.5 mg/mL (ultrasonic)

Smiles

NC(C([2H])([2H])C([2H])([2H])[C@@](N)([2H])C(O)=O)=O

Molecular Formula

C5H5D5N2O3

Molecular Weight

151.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Mary Corless , et al. Glutamine Regulates Expression of Key Transcription Factor, Signal Transduction, Metabolic Gene, and Protein Expression in a Clonal Pancreatic Beta-Cell Line. J Endocrinol. 2006 Sep;190 (3) :719-27.|[3]Newsholme P, et al. Glutamine and glutamate as vital metabolites. Braz J Med Biol Res. 2003 Feb;36 (2) :153-63. Epub 2003 Jan 29.