ITK inhibitor 2
ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor extracted from patent WO2011065402A1, compound 4, with an IC50 of 2 nM.
Product Specifications
CAS Number
[1309784-09-5]
UNSPSC
12352005
Target
Itk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/itk-inhibitor-2.html
Purity
99.50
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1(CC2=C(C(C3=CC4=CC=C(N(C)C([C@@H](N5CCOCC5)C)=O)C=C4N3)=NN2)CC1)C
Molecular Formula
C25H33N5O2
Molecular Weight
435.56
References & Citations
[1]Teruhiko Inoue, et al. Indole compounds and their pharmaceutical use.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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