NHS-PEG2-SS-PEG2-NHS

NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nhs-peg2-ss-peg2-nhs.html

Purity

98.03

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(ON1C(CCC1=O)=O)CCOCCOCCSSCCOCCOCCC(ON2C(CCC2=O)=O)=O

Molecular Formula

C22H32N2O12S2

Molecular Weight

580.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Disulfide Cleavable Linker

Available Sizes

Curated Selection

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