8-Hydroxy-2'-deoxyguanosine
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
Product Specifications
CAS Number
[88847-89-6]
Product Name Alternative
8-Oxo-2-Deoxyguanosine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-Amino-9-__2R,4S,5R_-4-hydroxy-5-_hydroxymethyl_tetrahydrofuran-2-yl_-3H-purine-6,8_7H,9H_-dione.html
Purity
99.61
Solubility
DMSO : 155 mg/mL (ultrasonic)
Smiles
O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3NC2=O)O[C@@H]1CO
Molecular Formula
C10H13N5O5
Molecular Weight
283.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG) : A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27 (2) :120-39.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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