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SMARCA-BD ligand 1 for PROTAC (hydrochloride)

Product Specifications

UNSPSC Description

SMARCA-BD ligand 1 hydrochloride for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].

Target Antigen

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/smarca-bd-ligand-1-for-protac-hydrochloride.html

Purity

99.23

Solubility

DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

OC1=CC=CC=C1C2=NN=C(N)C(N3CCNCC3)=C2.[H]Cl

Molecular Weight

307.78

References & Citations

[1]Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-44012B/SMARCA-BD-ligand-1-for-PROTAC-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-44012B/SMARCA-BD-ligand-1-for-PROTAC-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2380272-56-8

Available Sizes

Curated Selection

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