Scutellarin
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1 (74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively.
Product Specifications
CAS Number
27740-01-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; HIV; STAT
Type
Natural Products
Related Pathways
Anti-infection; JAK/STAT Signaling; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Scutellarin.html
Purity
99.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3C(O)=O)=C4O)C2=C4O
Molecular Formula
C21H18O12
Molecular Weight
462.36
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV-1; STAT3
Available Sizes
Frequently Asked Questions
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