FKBP12, Mouse (His)
Product Specifications
UNSPSC Description
The FKBP12 protein is multifunctional and critical in TGF-β signaling by maintaining TGFBR1 in an inactive conformation, thereby preventing receptor activation in the absence of ligand. It recruits SMAD7 to ACVR1B, blocks the binding of SMAD2 and SMAD3 to the activin receptor complex, and thereby inhibits activin signaling. FKBP12 Protein, Mouse (His) is the recombinant mouse-derived FKBP12 protein, expressed by E. coli , with N-His labeled tag. The total length of FKBP12 Protein, Mouse (His) is 107 a.a., with molecular weight of ~13 KDa.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/fkbp12-protein-mouse-his.html
Purity
98.0
Smiles
GVQVETISPG DGRTFPKRGQ TCVVHYTGML EDGKKFDSSR DRNKPFKFTL GKQEVIRGWE EGVAQMSVGQ RAKLIISSDY AYGATGHPGI IPPHATLVFD VELLKLE
Molecular Weight
Approximately 13 kDa
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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