Emixustat
Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1][2][3][4].
Product Specifications
CAS Number
[1141777-14-1]
Product Name Alternative
ACU-4429
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
RPE65
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Emixustat.html
Purity
98.74
Solubility
DMSO : ≥ 43 mg/mL|Ethanol : 100 mg/mL (ultrasonic)
Smiles
O[C@H](CCN)C1=CC(OCC2CCCCC2)=CC=C1
Molecular Formula
C16H25NO2
Molecular Weight
263.38
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19720/Emixustat-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19720/Emixustat-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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