PROTAC IRAK4 ligand-1
PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4 (IRAK4) . PROTAC IRAK4 ligand-1 can be used in the synthesis of PROTAC IRAK4 degrader-1 (HY-129966) [1].
Product Specifications
CAS Number
[2357108-39-3]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-irak4-ligand-1.html
Purity
99.49
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC(F)(F)C1=NN(C=C1NC(C2=COC(C3=CC=NC(N(C(OC(C)(C)C)=O)CC4CC4)=C3)=N2)=O)C5=CC=C(C(O)=O)C=C5
Molecular Formula
C29H27F3N6O6
Molecular Weight
612.56
References & Citations
[1]Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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