DAM-IN-1

DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor, IC50: 48 μM. DMA-IN-1 inhibits Caulobacter growth with an MIC of 35 μM[1].

Product Specifications

CAS Number

[935279-95-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dam-in-1.html

Purity

97.57

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC(=O)C1C2CC=CC2C3=C(N1)C=CC(=C3)C(=O)O

Molecular Formula

C16H17NO4

Molecular Weight

287.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Mashhoon N, et al. Selective inhibitors of bacterial DNA adenine methyltransferases. J Biomol Screen. 2006 Aug;11 (5) :497-510.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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