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Fisetin

Product Specifications

UNSPSC Description

Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.

Target Antigen

PPAR; Sirtuin; TNF Receptor

Type

Natural Products

Related Pathways

Apoptosis;Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Fisetin.html

Purity

99.99

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC=C13

Molecular Weight

286.24

References & Citations

[1]Kim SC, et al. Fisetin induces Sirt1 expression while inhibiting early adipogenesis in 3T3-L1 cells. Biochem Biophys Res Commun. 2015 Nov 27;467(4):638-44.|[2]Mukhtar E, et al. Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells. Cancer Lett. 2015 Oct 28;367(2):173-83.Acta Pharmacol Sin. 2023 May 24.|Aging (Albany NY). 2021 Nov 25;13(22):24753-24767.|Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.|Biochim Biophys Acta Mol Basis Dis. 2024 Sep 13:167515.|bioRxiv. 2024 Jul 30:2024.07.29.605645.|Cells. 2022, 11(13), 1992.|Eur J Pharmacol. 2023 Dec 23, 176298.|Hepatob Pancreat Dis. 2021 May 8.|J Ethnopharmacol. 2024 Jun 14:118421.|J Mol Liq. 23 November 2021, 118164.|J Nutr Biochem. 2023 Sep 23;109452.|Journal of Harran University Medical Faculty. 2023 Sep 6.|Molecules. 2023 Jul 20, 28(14), 5533.|Nat Aging. 2024 Apr;4(4):527-545.|Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 20.|Research Square Preprint. 2023 Nov 20.|Int J Mol Sci. 2024 Mar 27;25(7):3724.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0182/Fisetin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0182/Fisetin-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

528-48-3

Available Sizes

Curated Selection

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