Dodoviscin A
Dodoviscin A is a pigmentation-altering agent, which can be isolated from the aerial parts of Dodonaea viscosa. Dodoviscin A inhibits melanin production in B16-F10 melanoma cells. Dodoviscin A suppresses mushroom tyrosinase activity, and tyrosinase activity induced by 3-isobutyl-1-methylxanthine. Dodoviscin A also inhibits the phorphosylation of cAMP response element binding protein, induced by 3-isobutyl-1-methylxanthine and forskolin[1].
Product Specifications
CAS Number
1372527-25-7
UNSPSC
12352005
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dodoviscin-a.html
Solubility
10 mM in DMSO
Smiles
O=C1C(OC)=C(C2=CC(CCC(C)CO)=C(O)C(CC(O)C(C)=C)=C2)OC3=CC(O)=C(OC)C(O)=C13
Molecular Formula
C27H32O9
Molecular Weight
500.54
References & Citations
[1]Yan G, et al. Dodoviscin a inhibits melanogenesis in mouse b16-f10 melanoma cells. Planta Med. 2013 Jul;79 (11) :933-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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