(S)-AM-9022
Product Specifications
UNSPSC Description
(S)-AM-9022 is the S-enantiomer of AM-9022 (HY-162110). AM-9022 is an orally active, potent, selective KIF18A inhibitor that can be used for research on cancer[1].
Target Antigen
Kinesin; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-am-9022.html
Smiles
O=C(C1=CC=C(NS([C@@H](C)CO)(=O)=O)C=C1N2CCC3(CC3)CC2)NC4=CC(C)=NC(N5CCC(F)(F)CC5)=N4
Molecular Weight
578.67
References & Citations
[1]Payton M, et al. Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nat Cancer. 2023 Dec 27.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162110A/S-AM-9022-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162110A/S-AM-9022-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2446872-47-3
Available Sizes
Curated Selection
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