Tyrosinase-IN-37
Tyrosinase-IN-37 (Compound 3c) is an effective Tyrosinase inhibitor with an IC50 of 1.02 μM, exhibiting 14 times the inhibitory effect of kojic acid (Kojic acid, HY-W050154), which has an IC50 of 14.74 μM. Tyrosinase-IN-37 can effectively prevent the browning of Rosa roxburghii. Additionally, Tyrosinase-IN-37 can also inhibit browning that is not caused by Tyrosinase[1].
Product Specifications
CAS Number
1899025-43-4
UNSPSC
12352005
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-37.html
Smiles
CC1=CC=C(C2=NN(C3=NN=C(S)N3N)C=C2)C=C1
Molecular Formula
C12H12N6S
Molecular Weight
272.33
References & Citations
[1]Zhang J, et al. Development of novel pyrazole-1,2,4-triazole derivatives as tyrosinase inhibitors: Design, preparation, mechanism of action and anti-browning application. Food Chem. 2024 Dec 1;460 (Pt 3) :140722.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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