Biotin-Cel
Biotin-Cel (Celastrol-Biotin) is a biotin-labeled Celastrol (HY-13067) . Celastrol exhibits antitumor, anti-inflammatory, and anti-obesity activities. Biotin-Cel can be used in biotin-affinity pulldown assay to identify the molecular target of Celastrol in hepatocellular carcinoma cells[1].
Product Specifications
CAS Number
[2609685-71-2]
Product Name Alternative
Celastrol-Biotin
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-cel.html
Purity
96.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)C(NCCNC(CCCC[C@H]4[C@]5([H])[C@](NC(N5)=O)([H])CS4)=O)=O)C)(CC[C@@]6(C2=CC=C7C6=CC(C(O)=C7C)=O)C)C
Molecular Formula
C41H58N4O5S
Molecular Weight
718.99
References & Citations
[1]Du S, et al., Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells. Sci Rep. 2020 Jul 9;10 (1) :11273.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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